tina huang data scientist tina huang data scientist

There is no biographical data to display. Evol. The end goal is to create and grow a product that users love. b, Allele frequencies of different hunter-gatherer groups (coloured dots) on four SNPs related to skin colour (SLC24A5 and SLC45A2), eye colour (HERC2/OCA2) and lactase persistence (LCT). 7,794 followers. The error bar shows the s.e.m. Google Scholar. 116, 105100 (2020). The emergence of hunter-gatherer pottery in the Urals and West Siberia: new dating and stable isotope evidence. Genome Res. Ideally, we also want lots of data because this will give us more confidence in our results. The analysed individuals span from the Upper Palaeolithic to the Neolithic. 14, evac045 (2022). Besides El Mirn, who has around 43% Villabruna ancestry, all other Magdalenian-associated individuals have a lower proportion of this component (1929%) and can thus be assigned to the GoyetQ2 cluster (Fig. In the box plot the centre line is the median, box bounds delineate the interquartile range and whiskers extend to maximum and minimum values, excluding outliers. For ds_halfUDG libraries, we called genotypes on all targeted sites from 2bp-masked bam files; for ds_nonUDG libraries, we called genotypes on transversion sites only; for ss_nonUDG libraries, we called genotypes with single-strand mode, which ignores forward reads at C/T polymorphisms and reverse reads at G/A polymorphisms. & Dolukhanov, P.) 122145 (Avebury, 1993). USA 116, 16391644 (2019). 2. Science 344, 747750 (2014). The Solutrean culture is temporally intermediate between the Gravettian and the Magdalenian (or the Badegoulian) cultures, and is found in southwestern and western Europe, which are considered to have been climatic refugia for human populations during the LGM25,26. 864358 (to K.M. At this startup dedicated to b2b marketing, we, the data team formed by 2 people, are organizing all the data from zero and looking for their real value. Purchasing this course makes it your own. A recent bottleneck of Y chromosome diversity coincides with a global change in culture. Save my name, email, and website in this browser for the next time I comment. 32, 17921797 (2004). Utilized python and R on high performance computing Linux cluster to discover 3 new cancer mutations. This raises the possibility that the replacement by the Oberkassel cluster and the formation of the Sidelkino cluster might have been the result of population expansions influenced by the abrupt warming during the BllingAllerd interstadial4,24. Then we combined our newly generated genotypes with published genotypes from ancient and modern individuals from AADR v42.4 (Allen Ancient DNA Resource (https://reich.hms.harvard.edu/allen-ancient-dna-resource-aadr-downloadable-genotypes-present-day-and-ancient-dna-data) version 42.4) for downstream analysis1,4,7,14,16,23,36,37,38,39,40,42,43,45,79,80,81,82,83,84,85,86,87,88,89,90,91,92,93,94. J. University Universit Chouaib Doukkali; . In conclusion, our study reveals that western and southwestern Europe served as climatic refugia for the persistence of human groups during the coldest phase of the last Ice Age whereas populations in the Italian peninsula and the eastern European plain were genetically overturned, challenging the role of these regions as glacial refugia for humans. Biotechniques 59, 8793 (2015). Wood, R. E. et al. Narasimhan, V. M. et al. For the SNP associated with light eye colour (HERC2/OCA2 (rs12913832)), individuals from the Villabruna cluster,Oberkasselcluster, Baltic HG and SHG groups show high frequencies of the derived allele (>90%), which is responsible for the green or blue eye phenotype, whereas Sidelkinocluster, Ukraine HG and Iron Gates HG groups show low occurrence of this allele (1025%). In other words, youll never have to worry about validity issues or having to re-take the course after a certain amount of time. Natural Language Processing (NLP) is another technique that has a well-deserved position in product development. The f4-statistics were calculated by qpDstat 755 with parameter f4 mode: YES, with the Mbuti.DG population from Africa used as outgroup in all f-statistics analyses. Seguin-Orlando, A. et al. Much attention has b Fluorescent probes targeting specific organelles are useful tools for understanding their intracellular behaviors. The competition is based on a pretty strict data set thats been collected by the Stanford Computer Science department. Next, we investigated the genetic relationships between Epigravettian-associated individuals across the Italian peninsula, by reconstructing a phylogeny based on a matrix of pairwise f2 genetic distances (Fig. Evol. Natl Acad. F4-statistics also show that the approximately8.2ka Yuzhniy Oleniy Ostrov group from Karelia in western Russia formed by 19 genomes has comparable or lower affinity to Villabruna ancestry than all the other EHG groups (Supplementary Data 2.K). To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. Protoc. In particular, the 13ka Pradis 1 individual from northeastern Italy represents the most basal lineage compared to all other Epigravettian-associated individuals, including the older Tagliente 2 and Villabruna genomes from northern Italy (group 1). Nucleic Acids Res. CAS Lazaridis, I. et al. & Zimmermann, A. Evol. Quat. Hunter-gatherers carrying an admixed WHG/EHG genetic profile have been sequenced from various regions of northern and eastern Europe, raising the question of how these two types of ancestries formed and interacted with each other through time and space37,38,39,40. Evol. PLoS ONE 14, e0217996 (2019). Tina Huang. Dev. 31, 24842493.e7 (2021). Jones, E. R. et al. Biol. On the basis of f4-statistics, we find that individuals assigned to the Oberkassel cluster are closer to the Arene Candide 16 genome than any other Epigravettian-associated group from Italy (Supplementary Data 2.F). Curr. She was not prepared for the complexity of a typical programming language. The analysis of biological relatedness was performed by calculating relatedness coefficient (r) based on PMR on the autosomal SNPs (Supplementary Data 1.F and Supplementary Information, section4). Nature 592, 253257 (2021). My name is Tina and I'm a data scientist and YouTuber. In the video above, she explains the two major components of big data: data warehousing and data science. a, Population structure among Epigravettian-associated populations revealed by a neighbour-joining tree based on pairwise f2 genetic distances. The bivariate plots show the expansion of Oberkassel and Sidelkino ancestries through time in two European areas (longitude below and above 30 degrees). Yang, M. A. et al. The dates were calibrated using OxCal 4.452 with calibration curve IntCal20 at 95.4% probability53 and when multiple dates were available for the same individual we used the function R_Combine to combine them52. Nat. Extended Data Fig. Highly Influential Citations 3. This free online conference is featuring panel discussions from Newsletter, I also have a newsletter called Boop's Keyboard! Nature 582, 384388 (2020). and J.Krause performed or supervised genetic analyses. Highly recommended for not only people preparing for interviews but for people that just want to improve their coding skills. A subset of samples (GER002 and GER003) were pre-treated with a washing step to reduce surface contamination54. The cleaned reads with base quality and mapping quality over 30 were piled up with mpileup in SAMtools 1.373 on the 1240k targeted sites. Ruiz-Redondo, A. et al. Mateja Hajdinjak, Fabrizio Mafessoni, Svante Pbo, D. M. Fernandes, D. Strapagiel, R. Pinhasi, Pavel Flegontov, N. Ezgi Altnk, Stephan Schiffels, Daniel M. Fernandes, Kendra A. Sirak, David Reich, Sandra Oliveira, Kathrin Ngele, Mark Stoneking, Eirini Skourtanioti, Harald Ringbauer, Philipp W. Stockhammer, Vanessa Villalba-Mouco, Marieke S. van de Loosdrecht, Wolfgang Haak, Joseph H. Marcus, Cosimo Posth, John Novembre, Natalija Kashuba, Emrah Krdk, Anders Gtherstrm, Nature Extended Data Fig. BMC Bioinformatics 15, 356 (2014). Now we have Areej AbuAli, an SEO manager and the founder of Women in Tech SEO. 2932 and Supplementary Table 4). This course is presenting itself as both a refresher and a challenge. Edgar, R. C. MUSCLE: multiple sequence alignment with high accuracy and high throughput. Great content - Tina is all class and an excellent instructor. Tina Huang Profile page. Definitely a course worth investing in as it sticks out as a unique course focusing on SQL interviews and doesn't contribute to the abundance of generic courses on the internet! In anticipation of possible near-term approval from the US Food and Drug Administration for renal denervation, there must be an insistence on longer-term clinical outcomes and safety data. How to Become a Data Scientist at FAANG (Ft. Tina Huang) In this video, I had the opportunity to talk with Tina Huang, a Data Scientist at one of the FAANG companies. Develped strategies for promoting G-Mark to Taiwan. CNRS, MNHN, Universit de Paris Cit, Muse de lHomme, Paris, France, PALEVOPRIM Lab UMR 7262 CNRS-INEE, University of Poitiers, Poitiers, France, Centre de Valorisation des Collections Scientifiques, Universit de Poitiers, Mignaloux Beauvoir, France, Muses de PoitiersVille de Poitiers, Poitiers, France, Departamento de Geologa, Facultad de Ciencia y Tecnologa, Universidad del Pas Vasco/Euskal Herriko Unibertsitatea (UPV/EHU), Leioa, Spain, Sociedad de Ciencias Aranzadi, Donostia-San Sebastian, Spain, Centro UCM-ISCIII de Investigacin sobre Evolucin y Comportamiento Humanos, Madrid, Spain, Institute of Archaeology, University of Rzeszw, Rzeszw, Poland, Foundation for Rzeszw Archaeological Centre, Rzeszw, Poland, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA, Department of Psychiatry, Harvard Medical School, Boston, MA, USA, Groninger Instituut voor Archeologie, Groningen University, Groningen, The Netherlands, Institute of Archaeology and Ethnology, Polish Academy of Science, Pozna, Poland, Institute of History, Archaeology and Ethnography, Dushanbe, Tajikistan, ArchaeoZOOlogy in Siberia and Central AsiaZooSCAn, CNRSIAET SB RAS International Research Laboratory, IRL 2013, Institute of Archaeology SB RAS, Novosibirsk, Russia, Research Institute and Museum of Anthropology, Moscow State University, Moscow, Russia, Grupo de I+D+i EVOADAPTA (Evolucin Humana y Adaptaciones durante la Prehistoria) Departamento de Ciencias Histricas, Universidad de Cantabria, Santander, Spain, Borja Gonzlez-Rabanal,Ana B. Marn-Arroyo&Lawrence G. Straus, Instituto Internacional de Investigaciones Prehistricas de Cantabria (IIIPC), Universidad de Cantabria-Gobierno de Cantabria-Banco Santander, Santander, Spain, Departamento de Biologa de Organismos y Sistemas, Universidad de Oviedo, Oviedo, Spain, Quaternary Environments and Humans, OD Earth and History of Life, Royal Belgian Institute of Natural Sciences, Brussels, Belgium, Caroline Polet,Ivan Jadin&Sbastien Villotte, Muses Royaux dArt et dHistoire, Bruxelles, Belgium, Institute of Historical Research, University of Girona, Catalonia, Spain, Joaquim Soler,Neus Coromina&Isaac Ruf, INRAP/UMR 8215 Trajectoires 21, Paris, France, School of Human Evolution and Social Change, Arizona State University, Tempe, AZ, USA, Department of Anthropology, University of New Mexico, Albuquerque, NM, USA, GoArchPal-GoArchon, Viville sous-les-Cotes, France, Archologie & Mnzkabinett, Universalmuseum Joanneum, Graz, Austria, Museum Das Dorf des Welan, Wllersdorf-Steinabrckl, Austria, Department of Humanities, University of Ferrara, Ferrara, Italy, National Museum of Antiquities, Leiden, The Netherlands, Faculty of Archaeology, Leiden University, Leiden, The Netherlands, Biogeology, Department of Geosciences, University of Tbingen, Tbingen, Germany, Unit de Recherches Art, Archologie Patrimoine, Universit de Lige, Lige, Belgium, I.U. This often involves analyzing similar products to compare how they performed. Protoc. 4a and Supplementary Data 3.C). Dismiss. Tina Huang, a data scientist currently working at a FAANG (Facebook, Amazon, Apple, Netflix, and Google Alphabet) company. Patterson, N. et al. Radiocarbon 51, 337360 (2009). When Gravettian-associated individuals are included in an admixture graph also featuring Kostenki 14, we find that Fournol 85 fits best as a sister lineage of Goyet Q116-1, whereas the Vstonice group is modelled as a mixture between a lineage related to the Sunghir group and one related to the Goyet Q116-1Fournol 85 branch (Fig. 5). Straus, L. G. The human occupation of southwestern Europe during the Last Glacial Maximum: Solutrean cultural adaptations in France and Iberia. Science 366, 708714 (2019). Runtime Collective Limited (trading as Brandwatch). 1925). Maier, A. in The Central European Magdalenian 81180 https://doi.org/10.1007/978-94-017-7206-8_6 (Springer, 2015). Data warehousing is a relatively new field that focuses on the use of large datasets for analytical purposes. Curr. Additional details are provided in SupplementaryInformation, section11 and SupplementaryTable 3. Product development is, by far, my favorite data science use case for two main reasons. These f4-statistics also confirm that Goyet Q376-3 carries a similar ancestry to Goyet Q116-1 and Kostenki 12 carries a similar ancestry to the Sunghir group, whereas Bacho Kiro 1653 (35ka) from Bulgaria, Muierii 1 (34ka) and Cioclovina 1 (32ka) from Romania, and Paglicci 133 (33ka) from southern Italy are equally related to Goyet Q116-1 and Sunghir. Initial Upper Palaeolithic humans in Europe had recent Neanderthal ancestry. While terms such as lithic industry, techno-complex, prehistoric tradition, and so on might be more appropriate to refer to the various associated chrono-cultural subdivisions, they concern different levels of discussion and are not applicable to all contexts investigated here. Goutas, N. in Les Gravettiens (ed. Genet. The dimensions are calculated using newly reported and previously published hunter-gatherer groups or individuals with more than 30,000 SNPs. This suggests that genetic links between southern and southwestern European hunter-gatherers around the time of the LGM extended north of the Pyrenees. Peltzer, A. et al. The mapped reads from the same individual and library set-up were merged and duplications were removed with DeDup. 9). 1a, and the y-axes report time in thousand years before present (kBP). (2023, March 1). J. Anthropol. We generated genome-wide sequencing data for 102 newly reported hunter-gatherers, and increased coverage for 14 previously published individuals4. Adv. This results in a tree with 57 newly reported and previously published ancient individuals while present-day sequences are collapsed in the major Y-chromosome haplogroups (the most basal lineages are not shown). For consistency with the previously discussed nomenclature, we rename the EHG ancestryas the Sidelkino cluster(hereafter, Sidelkino cluster or ancestry). Gnther, T. et al. Further palaeogenomic studies on Upper Palaeolithic individuals from the Balkans will be essential for understanding whether southeastern Europe represents the source of the Villabruna ancestry and a climatic refugium for human populations during the LGM. 1). Epoxy Flooring UAE; Floor Coating UAE; Self Leveling Floor Coating; Wood Finishes and Coating; Functional Coatings. About the author: Tina Huang is a data scientist at one of the FAANG companies. Gronenborn, D. in The Spread of the Neolithic to Central Europe (RGZM, 2010). The authors thank G. Marciani and O. Jris for comments on archaeology; C. Jeong, M. Spyrou and K. Prfer for comments on genetics; M. OReilly for graphical support for Fig. ADS Genetics 203, 881891 (2016). The labels in italic denote previously published individuals without new data generated in this study. Along with pushing for more accessibility, she also creates content around working in the tech industry, the challenges that come with it, and career advice. 26 and Supplementary Data 2.H). By contrast, the Goyet Q116-1 genetic profile gave rise to the newly described Fournol cluster identified in Gravettian-associated individuals from western and southwestern Europe. and T. Saupe received support from the European Union through the European Regional Development Fund (project no. eLife 11, e77625 (2022). The Kostenki genetic signature (related to the Kostenki 14 genome, and hereafter referred to as the Kostenkicluster or ancestry) contributed to the later Vstonice genetic cluster(hereafter,Vstonice cluster or ancestry), named after the Doln Vstonice site in Czechia4. "Presumably, these people came from the Balkans, arrived first in northern Italy around the time of the glacial maximum and spread all the way south to Sicily.". Rohland, N. & Hofreiter, M. Ancient DNA extraction from bones and teeth. Write a sharp and effective resume in minutes and get noticed by employers. Your email address will not be published. During this time agriculture and a sedentary lifestyle spread from Anatolia to Europe. After the LGM, the Epigravettian culture was widespread in southern andsoutheastern Europe. Other individuals from that period, such as Zlat k from Czechia and UstIshim from Russia, do not carry significantly more Neanderthal ancestry than other non-African groups1,7, indicating differential interactions between Neanderthals and early modern humans during their initial expansions across Eurasia. Tina Llorca CPA, CWP, CEPP, CIS, MDRT Ampliar bsqueda. Negative and positive controls were carried alongside each experiment. Extended Data Fig. In central-western Europe, Gravettian-associated individuals from Goyet show affinity to both clusters. The membrane was able to achieve FRR of 98.73 0.83 % after 4 cycles of filtration, indicating that anti-fouling properties have been enhanced. I worked in bioinformatics in cancer research and then decided to a masters in computer science (MCIT) from the University of . Science 365, eaat7487 (2019). 3b). Wow! The course is well structured and just what one needs before preparing for a data science interview with focus on SQL.